Overnutrition is a bad eating habit that has been linked to increased health risks, particularly in wealthy countries. As a result, there is a discrepancy between energy storage and energy breakdown. Many biochemical mechanisms including hormones are implicated in the transmission of surplus energy into pathological states, including atherosclerosis, hypertension, cardiovascular disease, and diabetes. Various forms of regular exercise have been demonstrated to be useful in resolving the over nutrition comorbidities to varying degrees. Hormesis, or cellular workouts, are induced by dietary programmes and may underpin the cellular processes that modulate the harmful consequences of over nutrition by activating certain cellular signal pathways.