Since the transplanted heart originates from another organism, the recipient's system typically attempts to reject it. The danger of rejection never fully goes away, and therefore the patient are going to be on immunosuppressive drugs for the remainder of their life. These drugs may cause unwanted side effects, like increased likelihood of infections or development of certain cancers. Recipients can acquire renal disorder from a heart transplant thanks to the side effects of immunosuppressant medications. Many recent advances in reducing complications thanks to tissue rejection stem from mouse heart transplant procedures.